Industry 4.0, a concept comprising a range of promising innovations enabled by the recent advancements in digital technologies, has become a priority of industrial policy in many European countries and regions. In this paper, we present actions undertaken by regional organisations (including the so-called Digital Innovation Hubs), fostering the adoption of Industry 4.0 technologies in manufacturing companies. Using examples from Germany, Italy and Poland, we show actions that enable the creation of general conditions for such implementations and help companies develop an individual strategy for adopting Industry 4.0 innovations.