One of the economic policies used by governments for local and regional development is the encouragement of entrepreneurship through business incubators, which contribute to the creation of companies and employment, increase business survival rates and the payment of taxes and social contributions to public administration. However, they are consumers of external resources and have a high dependence on the Public Sector. In this study we analyse the net contribution of these business initiative centres in Galicia (Spain) through the use of the «Integral Model of profitability of business incubators» based on structural equations.