During last years, a central issue of theory debate and economic policy is clearly manufacture clusters and the local capabilities which take part,promote and condition its competitiveness. This article analyzes two local experiences in Argentina —the Agricultural Machinery District and Las Parejas Cluster— connecting topics such as innovation, learning and other difficulties (endogenous and exogenous), which disturb the normal cluster operations of local industrialized agglomerations. From this perspective, innovation processes, firm relationships and institutional network actions are analyzed. This study concludes with some associations which identify similar local trajectories from others periphery experiences.