In this work we go through the economic literature that has quantified in the last years the macroeconomic effects of public infrastructures at the regional level. The paper offers, from the point of view of the authors, a review of the most significant contributions to the production function and cost function approaches. In the analysis we put the emphasis on results obtained for the Spanish economy. Likewise, the conclusions are entirely devoted to extract recommendations, that should be taken in mind, when designing public investment policies of infrastructure endowment in Spain.